Chemicals in plastics linked to newborn deaths and premature births

A study published in eClinicalMedicine reports that two phthalates, DEHP and DINP, were estimated to be linked to millions of premature births and tens of thousands of newborn deaths worldwide in 2018.

A study published in the journal eClinicalMedicine reports links between two plastic additives and adverse birth outcomes. Researchers examined di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DINP) using 2018 data. The study provides global estimates of premature births and newborn deaths associated with those chemicals. The authors note broader health concerns tied to phthalates and refer to ongoing policy discussions about regulation. Key findings: - The study estimated DEHP was linked to about 1.97 million premature births in 2018, representing about 8.74% of premature births, and to an estimated 74,000 newborn deaths that year. - The study estimated DINP was linked to about 1.88 million premature births and an estimated 64,000 newborn deaths in 2018. - Phthalates are commonly used in personal care products, children’s toys, and food packaging and processing materials, and have been reported to disrupt hormone function and to be associated with a range of health concerns. - The study’s authors noted that treaty negotiations to regulate phthalates are moving forward and called for further assessment of costs and consideration of stronger regulatory measures for phthalates as a class. Summary: The published analysis presents large-scale estimates tying DEHP and DINP to premature births and newborn deaths based on 2018 data and reiterates known health concerns about phthalates. Negotiations to regulate phthalates are reported to be underway; specific next steps and timelines are undetermined at this time.