Supplements may change health outcomes in later life

A Mass General Brigham study reported that multivitamins were associated with slower biological ageing in people over 70, and experts highlighted common nutrient shortfalls in later life while naming omega‑3, vitamin D with K2, B vitamins, magnesium and NMN as frequently discussed supplements.

Many people think about supplements when planning a healthier lifestyle, especially as they age. Older adults can have greater needs for certain vitamins and minerals and may face practical barriers to getting a varied diet. A Mass General Brigham study reported that multivitamins were linked with slower biological ageing in people over 70. The article also presents a range of expert views on benefits, risks and common nutrient shortfalls. Key points: - A trial by Mass General Brigham analysed DNA from 958 participants with an average age near 70 and found that those taking multivitamins showed about four months less biological ageing over two years compared with placebo. - Experts cited common shortfalls in later life, including vitamin D, vitamin B12, folate and magnesium. - The article highlights five supplements discussed by specialists: omega-3, vitamin D with K2, B vitamins, magnesium and NMN, and notes that evidence and safety information vary between them. - Clinicians warned against indiscriminate or excessive supplement use; the article cites excess vitamin A as an example of a potential harm linked to bone fracture risk. - Some nutrient levels (for example vitamin D or iron) can be measured by blood tests, but routine testing for all supplements is described as costly or impractical. Summary: The study and expert commentary suggest supplements can help address common nutrient gaps in older adults and may have modest associations with biological markers. The article reports differing evidence levels and cautions about overuse, and does not present a single clinical recommendation. Undetermined at this time.