Collagen supplements improve skin elasticity and hydration but do not erase wrinkles

A large umbrella review found daily collagen supplementation was linked to modest improvements in skin elasticity and hydration but did not show convincing reductions in wrinkles; the analysis pooled 16 systematic reviews and more than 100 randomized trials.

An umbrella review led by Anglia Ruskin University examined the strongest available evidence on collagen supplements and skin outcomes. The researchers reviewed 16 systematic reviews that together covered 113 randomized controlled trials and 7,983 participants, using studies indexed through March 2025. The team assessed effects across skin, musculoskeletal, oral and cardiometabolic outcomes and graded evidence strength with established criteria. For skin, they reported modest gains in elasticity and hydration with consistent, long-term use but no convincing reduction in wrinkles or skin roughness. Key findings: - The review pooled 16 systematic reviews covering 113 randomized controlled trials and 7,983 participants worldwide. - Daily collagen supplementation taken over time was associated with improved skin elasticity and hydration. - The analysis found no convincing evidence that collagen reduces wrinkles or substantially improves skin roughness. - Collagen supplements were also linked to reduced joint pain and stiffness in some studies, notably in people with osteoarthritis. - Evidence for oral health and cardiometabolic measures was mixed and less conclusive. Summary: The review indicates collagen supplements can support deeper skin structure and offer modest benefits for elasticity and hydration while not reversing established facial lines. Undetermined at this time.